abstract：AIMS OF THIS STUDY:This study evaluated whether human cavernosal myofibroblasts in cell culture is a viable model for the study of the role of oxygen free radicals in the production of collagen types I and III, as observed in Peyronie's disease. METHOD:Human cavernosal cells in primary culture were incubated with 3H-p...

journal_title：International journal of impotence research

authors： Ahuja SK,Sikka SC,Hellstrom WJ

更新日期：1999-08-01 00:00:00

abstract：:Erectile dysfunction occurs frequently in humans with diabetes mellitus; the molecular basis of this phenomenon is not known. We investigated the effects of diabetes on penile erection, nitric oxide synthase and growth factors expression in an animal model. Forty male rats were divided into two groups: the experimenta...

journal_title：International journal of impotence research

authors： El-Sakka AI,Lin CS,Chui RM,Dahiya R,Lue TF

更新日期：1999-06-01 00:00:00

abstract：:Tunica albuginea (TA) of the penis, which has an important role in mechanism of erection, is composed mainly of collagen bundles. Both aging and diabetes mellitus (DM) were reported to be associated with many alterations in collagen content and architecture in several body tissues. So, the aim of this work was to eval...

journal_title：International journal of impotence research

authors： Salama N,Kagawa S

更新日期：1999-04-01 00:00:00

abstract：:The aim of this work is evaluate the efficacy of infection control measures with unicomponent penile implants in two ambulatory surgery units in Cairo and Jeddah. This was a retrospective study of 117 consecutive cases. A patient selection and infection control protocol was followed to implant 12 hydraulic, 53 mechani...

journal_title：International journal of impotence research

authors： Ghanem HM,Fahmy I,Fallon B

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:Quality of life (QOL) data were used to evaluate the effects of self-administered intracavernosal injection of alprostadil for erectile dysfunction, when used for up to 18 months during a 13 country Phase III clinical trial. METHODS:The Duke Health Profile was used to measure patients' physical and psychoso...

journal_title：International journal of impotence research

authors： Willke RJ,Yen W,Parkerson GR Jr,Linet OI,Erder MH,Glick HA

更新日期：1998-12-01 00:00:00

abstract：:Sildenafil citrate has been shown to be effective in a wide range of patients with erectile dysfunction and has been approved in the United States for this indication. The overall clinical safety of oral sildenafil, a potent inhibitor of phosphodiesterase type 5, in the treatment of erectile dysfunction was evaluated ...

journal_title：International journal of impotence research

authors： Morales A,Gingell C,Collins M,Wicker PA,Osterloh IH

更新日期：1998-06-01 00:00:00

abstract：:At this present time there is a serious gap in our understanding of how psychological difficulties result in specific sexual dysfunction. In this paper, a theoretical model of sexual response is proposed which involves the parallel existence of excitatory and inhibitory mechanisms in the central nervous system. Eviden...

journal_title：International journal of impotence research

authors： Bancroft J

更新日期：1998-05-01 00:00:00

abstract：:The diagnosis and classification of female sexual disorders has undergone significant changes over the last fifty years as a function of changing societal expectations for female sexual conduct, available knowledge about sexual psychophysiology and actual clinical practice. Currently, female sexual disorders are conce...

journal_title：International journal of impotence research

authors： Leiblum SR

更新日期：1998-05-01 00:00:00

abstract：:The aim of the study was to determine whether any difference would occur in peak systolic velocity (PSV) and end diastolic velocity (EDV) measurements of color Doppler ultrasonography (CDU) between proximal and distal segments of the cavernous arteries obtained at different times. Twenty-six cases have undergone CDU t...

journal_title：International journal of impotence research

authors： Akkuş E,Alici B,Ozkara H,Ataus S,Bağişgil M,Hattat H

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The objective was to collect characteristics of patients with male erectile disorder (MED) attending a male sexual dysfunction clinic and determine the level of psychological morbidity whilst recruiting subjects into a psychotherapy study. METHODS:This was a study of data of 132 patients diagnosed as having...

journal_title：International journal of impotence research

authors： Wylie KR

更新日期：1997-12-01 00:00:00

abstract：:In extracavernosal vascular tissue, smooth muscle tone is modulated by a balance between angiotensin II (Ang II) and nitric oxide (NO). We hypothesized that these substances also play an important role in regulating cavernosal smooth muscle contractility. We therefore studied the in vitro effects of an Ang II receptor...

journal_title：International journal of impotence research

authors： Comiter CV,Sullivan MP,Yalla SV,Kifor I

更新日期：1997-09-01 00:00:00

abstract：:Several self-injection devices have been recently proposed as an aid to home intracavernosal self-injection treatment for erectile dysfunction, with the purpose of allowing an easier drug administration, decreasing the artificiality of intracavernosal pharmacotheraphy, with the overall goal of increasing the acceptabi...

journal_title：International journal of impotence research

authors： Pescatori ES,Calpista A,Artibani W,Pagano F,Calabro A

更新日期：1996-06-01 00:00:00

abstract：:Forty-four men aged 20-56 years (mean 42) complaining a venous erectile dysfunction underwent penile venous surgery. Fifteen patients (34.1%) were treated by DDVL, 29 cases (65.9%) underwent DDVL + corporopexy. All patients were followed-up at short and long-term periods. In short-term follow-up, eight patients (57.2%...

journal_title：International journal of impotence research

authors： Sasso F,Gulino G,Di Pinto A,Alcini E

更新日期：1996-03-01 00:00:00

abstract：:We evaluated the effects of chronic penile denervation on cavernous tissue morphology and function in 36 Sprague-Dawley rats. At age seven weeks, 18 animals underwent bilateral cavernous nerve neurectomy: 18 animals underwent sham operation as a control. A functional, biochemical and morphological assessment of the ra...

journal_title：International journal of impotence research

authors： Martínez-Piñeiro L,Dahiya R,Brock GB,Hsu GL,von Heyden B,Lue TF

更新日期：1995-09-01 00:00:00

abstract：:A prospective study was done on 76 patients who underwent surgical correction by corporeal plication of the penile deformity secondary to Peyronie's disease. Nocturnal penile tumescence and rigidity were recorded by RigiScan during three consecutive nights, before and after the operation. A significant number of patie...

journal_title：International journal of impotence research

authors： Claes H,Baert L

更新日期：1995-06-01 00:00:00

abstract：:The objective of this study was to evaluate the effect on erections of impeding venous blood flow following intracavernosal injections of prostaglandin E1. Dispersion of injected X-ray contrast medium indicated that application of the RMRI penile clamp to the base of the penis retarded venous outflow. The clamp was th...

journal_title：International journal of impotence research

authors： el-Saleh JC,Keogh EJ,Chew KK,Earle CM,Lee JL,Wearmouth JW

更新日期：1995-03-01 00:00:00

abstract：:Erectile dysfunction is a common disorder. However, not all dysfunctional men want to pursue evaluation. To delineate the characteristics of men interested in evaluation of erectile dysfunction, we conducted a mailed survey of 1031 randomly selected male veterans aged 30-99 years. We received 427 completed surveys. Us...

journal_title：International journal of impotence research

authors： Greenstein A,Chen J,Perez ED,Mulligan T

更新日期：1994-12-01 00:00:00

abstract：:Vibrotactile stimulation, when used in combination with visual sexual stimulation, has been shown to enhance erectile response in sexually functional men. The present study attempted to describe a diagnostic methodology, including the development and application of a new mini-vibrator, that might enhance penile respon...

journal_title：International journal of impotence research

authors： Rowland DL,den Ouden AH,Slob AK

更新日期：1994-09-01 00:00:00

abstract：:In a study on the diagnosis and treatment of erectile dysfunction (ED) in general practice, a self-selected sample of 90 general practitioners (GPs) (76 males, 14 females) from a predominantly urban population of 525 GPs were interviewed. It appeared that 59% would not actively interrogate a patient when an erection p...

journal_title：International journal of impotence research

authors： Broekman CP,van der Werff ten Bosch JJ,Slob AK

更新日期：1994-06-01 00:00:00

abstract：:A consecutive series of 52 men presenting with erectile dysfunction were assessed with (i) standardized sexual history, (ii) nocturnal penile tumescence and rigidity monitoring (NPTR), (iii) Rigiscan assessment of response to intracavernosal papaverine or prostaglandin injection (ICI), and (iv) duplex ultrasonography....

journal_title：International journal of impotence research

authors： Gutierrez P,Pye S,Bancroft J

更新日期：1993-09-01 00:00:00

abstract：:The release of mediator substances of the arachidonic acid cascade is closely related to the functional state of the endothelium. A significant lower prostacyclin/thromboxane A2 ratio in penile plasma of organogenic impotent patients in comparison to patients with psychogenic erectile dysfunction has been described in...

journal_title：International journal of impotence research

authors： Köhler H,Sohn M,Klein CL,Sikora R,Bosshardt R,Jakse G,Kirkpatrick CJ

更新日期：1993-03-01 00:00:00